Methods Validation
The Methods Validation Team critically reviews bioassays and related methods used in the development and evaluation of vector control tools to identify and minimise sources of variability and identify gaps in our knowledge of how best to perform testing for existing and new tools and analyse and interpret the results. We address these gaps by developing consensus protocols, experimentally validating existing and new methods, and engaging with stakeholders to identify concerns and generate solutions, which include best practice protocols and supporting documents and data analysis tools.
Recent Outputs
- Publication of the Method Validation Framework, a key development in the effort to generate consistent, high-quality data for evaluating control tools.
- Development of the Methods Landscape, documenting the current methods used to develop and assess vector control tools, inclusive of reports reviewing test methods to date, and a repository of best practice standard operating procedures for the laboratory and semi-field testing of vector control products from global testing sites.
- Publications on sources of variability in vector control bioassays.
- Continued contribution to WHO policy.
Current Activities
- Application of the Method Validation Framework to validate methods for operational research on novel vector control methods.
- Expansion of the vector control Methods Landscape to include new areas of interest and novel tools.
- Developing more standardised testing methodologies to minimise sources and scale of variability.
- Developing a new sample size framework for a range of widely used mosquito bioassay which will be accessible through easy-to-use applications.
- Novel bioassay development for dual-active ingredient products.
- Co-ordination of evaluation of ITN physical durability and testing methodologies to meet the requirements of the WHO Prequalification team.
